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Voxelotor

CAT: 0931-T7581-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T7581-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1446321-46-5
Target
Others
Related Pathways
Others
Purity
0.9994
Bioactivity
Voxelotor (GBT 440) is a novel hemoglobin S (HbS) polymerization inhibitor primarily used for the treatment of sickle cell disease (SCD) and a cytochrome P450 3A4 inhibitor. Voxelotor targets and covalently binds to the N-terminal valine of the HbS alpha chain, thereby stabilizing sickle cell hemoglobin (HbS) .
Smiles
CC(C)n1nccc1-c1ncccc1COc1cccc(O)c1C=O
Molecular Formula
C19H19N3O3
Molecular Weight
337.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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