PF-04691502
CAT:
804-HY-15177-06
Size:
50 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PF-04691502
- CAS Number: 1013101-36-4
- UNSPSC Description: PF-04691502 is a potent and selective inhibitor of PI3K and mTOR. PF-04691502 binds to human PI3Kα, β, δ, γ and mTOR with Kis of 1.8, 2.1, 1.6, 1.9 and 16 nM, respectively.
- Target Antigen: Autophagy; mTOR; PI3K
- Type: Reference compound
- Related Pathways: Autophagy;PI3K/Akt/mTOR
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/pf-04691502.html
- Solubility: DMSO : 50 mg/mL (ultrasonic)
- Smiles: OCCO[C@@H]1CC[C@@H](N2C(N=C(N)N=C3C)=C3C=C(C4=CC=C(OC)N=C4)C2=O)CC1
- Molecular Weight: 425.48
- References & Citations: [1]Yuan J, et al. PF-04691502, a potent and selective oral inhibitor of PI3K and mTOR kinases with antitumor activity. Mol Cancer Ther. 2011 Nov;10(11):2189-99.
- Shipping Conditions: Room Temperature
- Clinical Information: Phase 2