(-) -JNJ-A07

• Description :

  (-) -JNJ-A07 is a potent and selective DENV inhibitor with an EC50 value of 31 nM[1].

• UNSPSC :

  12352005

• Target :

  Flavivirus

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/minus-jnj-a07.html

• Concentration :

  10mM

• Purity :

  98.04

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  OC(CCCOC1=CC(OC)=CC(NC(C2=CC=C(C=C2)Cl)C(N3C4=CC(OC(F)(F)F)=CC=C4CC3)=O)=C1)=O.[Rotation(-)]

• Molecular Formula :

  C28H26ClF3N2O6

• Molecular Weight :

  578.96

• References & Citations :

  [1]Bart Rudolf Romanie Kesteleyn, et al. Substituted indoline derivatives as dengue viral replication inhibitors. WO2017167951 (compound 4A)

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2135640-92-3]