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Cefadroxil (hydrate) (Standard)

CAT: 0804-HY-B1190AR-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1190AR-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cefadroxil (hydrate) (Standard) is the analytical standard of Cefadroxil hydrate. This product is intended for research and analytical applications.
CAS Number
66592-87-8
Product Name Alternative
BL-S 578 (hydrate) (Standard)
UNSPSC
12352005
Target
Antibiotic; Bacterial; EAAT; Reference Standards
Type
Reference compound
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel; Others
Field of Research
Infection; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cefadroxil-hydrate-standard.html
Smiles
O=C(C(N12)=C(C)CS[C@]2([H])[C@H](NC([C@H](N)C3=CC=C(O)C=C3)=O)C1=O)O.O
Molecular Formula
C16H19N3O6S
Molecular Weight
381.40
References & Citations
[1]Buck RE, et al. Cefadroxil, a new broad-spectrum cephalosporin. Antimicrob Agents Chemother. 1977 Feb;11 (2) :324-30.|[2]Posada MM, et al. Relevance of PepT1 in the intestinal permeability and oral absorption of cefadroxil. Pharm Res. 2013 Apr;30 (4) :1017-25.|[3]Hu Y, et al. Species differences in the pharmacokinetics of cefadroxil as determined in wildtype and humanized PepT1 mice. Biochem Pharmacol. 2016 May 1;107:81-90.|[4]Han CJ, et al. Antinociceptive effects of cefadroxil and ceftriaxone in experimental animal models of pain. Neuro Endocrinol Lett. 2023 Jul 28;44 (5) :309-320.|[5]Tan Z, et al. Physiologically Based Pharmacokinetic Modeling of Cefadroxil in Mouse, Rat, and Human to Predict Concentration-Time Profile at Infected Tissue. Front Pharmacol. 2021 Dec 23;12:692741.|[6]Chisholm DR, et al. Therapeutic efficacy of cefadroxil and cephalexin for pneumonia in a rat test model. Antimicrob Agents Chemother. 1986 Jul;30 (1) :105-9.|[7]Chen X, et al. Influence of peptide transporter 2 (PEPT2) on the distribution of cefadroxil in mouse brain: A microdialysis study. Biochem Pharmacol. 2017 May 1;131:89-97.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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