Cefadroxil (Standard)

• Description :

  Cefadroxil (Standard) is the analytical standard of Cefadroxil (HY-B1190) . This product is intended for research and analytical applications. Cefadroxil is an orally active broad-spectrum cephalosporin antibiotic. Cefadroxil inhibits bacterial cell wall synthesis and enhances the expression of glutamate transporter-1. Cefadroxil is dependent on the intestinal peptide transporter PepT1 for small intestinal absorption. Cefadroxil has inhibitory and bactericidal activity against a variety of Gram-positive and Gram-negative bacteria and has analgesic effects on neuropathic pain[1][2][3][4][5][6][7][8].

• Product Name Alternative :

  BL-S 578 (Standard)

• UNSPSC :

  12352005

• Target :

  Antibiotic; Bacterial; EAAT; Reference Standards

• Type :

  Reference Standards

• Related Pathways :

  Anti-infection; Membrane Transporter/Ion Channel; Others

• Field of Research :

  Infection; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/cefadroxil-standard.html

• Purity :

  98.85

• Smiles :

  O=C(C(N12)=C(C)CS[C@]2([H])[C@H](NC([C@H](N)C3=CC=C(O)C=C3)=O)C1=O)O

• Molecular Formula :

  C16H17N3O5S

• Molecular Weight :

  363.39

• References & Citations :

  [1]Chen X, et al. Influence of peptide transporter 2 (PEPT2) on the distribution of cefadroxil in mouse brain: A microdialysis study. Biochem Pharmacol. 2017 May 1;131:89-97.|[2]Hu Y, et al. Species differences in the pharmacokinetics of cefadroxil as determined in wildtype and humanized PepT1 mice. Biochem Pharmacol. 2016 May 1;107:81-90.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C, sealed storage, away from light and moisture

• Scientific Category :

  Reference Standards

• CAS Number :

  [50370-12-2]