Cefadroxil-d4 (hydrate)

• UNSPSC Description:

  Cefadroxil-d4 (hydrate) is the deuterium labeled Cefadroxil. Cefadroxil is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections.

• Target Antigen:

  Antibiotic; Bacterial; Isotope-Labeled Compounds

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Anti-infection;Others

• Field of Research:

  Infection

• Solubility:

  10 mM in DMSO

• Smiles:

  OC(C1=C(C)CS[C@@]([C@@H]2NC([C@@H](C3=C([2H])C([2H])=C(C([2H])=C3[2H])O)N)=O)([H])N1C2=O)=O.O

• Molecular Weight:

  385.43

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Chen X, et al. Influence of peptide transporter 2 (PEPT2) on the distribution of cefadroxil in mouse brain: A microdialysis study. Biochem Pharmacol. 2017 May 1;131:89-97.|[3]Hu Y, et al. Species differences in the pharmacokinetics of cefadroxil as determined in wildtype and humanized PepT1 mice. Biochem Pharmacol. 2016 May 1;107:81-90.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1426174-38-0