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(Rac) -Anemonin

CAT: 0804-HY-N0278A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0278A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(Rac) -Anemonin ((Rac) -Pulsatilla camphor) is the diastereoisomer of Anemonin. Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases[1][2].
CAS Number
90921-11-2
Product Name Alternative
(Rac) -Pulsatilla camphor; (Rac) -Anemonine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
NO Synthase; PKC
Type
Natural Products
Related Pathways
Epigenetics; Immunology/Inflammation; TGF-beta/Smad
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/rac-anemonin.html
Purity
98.19
Solubility
10 mM in DMSO
Smiles
O=C1C=CC2(C3(CC2)C=CC(O3)=O)O1
Molecular Formula
C10H8O4
Molecular Weight
192.17
Precautions
H302, H315, H319, H335
References & Citations
[1]Jiang L, et al. Anti-inflammatory effects of anemonin on acute ulcerative colitis via targeted regulation of protein kinase C-θ. Chin Med. 2022 Mar 28;17 (1) :39.|[2]Lee TH, et al. Anemonin, from Clematis crassifolia, potent and selective inducible nitric oxide synthase inhibitor. J Ethnopharmacol. 2008 Mar 28;116 (3) :518-27.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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