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FR-190997

CAT: 0804-HY-123376Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-123376Size:1 Each
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Description
FR-190997 is a non-peptide Bradykinin B2 receptor selective agonist, Ki value is 9.8 nM. FR-190997 is also an effective antihypertensive agent[1].
CAS Number
193344-25-1
UNSPSC
12352005
Target
Bradykinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/fr-190997.html
Smiles
O=C(C1=CC=C(C=C1)/C=C/C(NCC(N(C)C2=CC=C(C(COC3=C4N=C(C=C(C4=CC=C3)OCC5=NC=CC=C5)C)=C2Cl)Cl)=O)=O)NC
Molecular Formula
C37H33Cl2N5O5
Molecular Weight
698.59
References & Citations
[1]Vachlioti E, et al. Development of a multigram synthesis of the bradykinin receptor 2 agonist FR-190997 and analogs thereof. Arch Pharm (Weinheim) . 2023 May;356 (5) :e2200610.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Bradykinin B2 Receptor (B2R)

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