Pomalidomide-CO-C3-PEG4-C6-NH2

Pomalidomide-CO-C3-PEG4-C6-NH2

• UNSPSC Description: Pomalidomide-CO-C3-PEG4-C6-NH2 is an E3 ligase ligand-linker conjugate part of PROTAC PIPIB degrader 1 (HY-158381). Pomalidomide consists of the E3 ligase ligand Pomalidomide (HY-10984) and a linker[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pomalidomide-co-c3-peg4-c6-nh2.html
• Smiles: NCCCCCCOCCOCCOCCOCCCCCC(NC1=C2C(C(N(C3C(NC(CC3)=O)=O)C2=O)=O)=CC=C1)=O
• Molecular Weight: 618.72
• References & Citations: [1]Yang Z, et al. Discovery of Selective Proteolysis-Targeting Chimera Degraders Targeting PTP1B as Long-Term Hypoglycemic Agents. J Med Chem. 2024 May 9;67(9):7569-7584.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported