Pomalidomide-PEG4-C2-NH2

Pomalidomide-PEG4-C2-NH2

• CAS Number: 2225940-52-1
• UNSPSC Description: Pomalidomide-PEG4-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/E3_Ligase_Ligand-Linker_Conjugates_22.html
• Purity: 95.11
• Solubility: DMSO : 50 mg/mL (ultrasonic)
• Smiles: O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCOCCOCCOCCN)=O
• Molecular Weight: 492.52
• References & Citations: [1]Jian Jin, et al. Compositions and methods for treating ezh2-mediated cancer. WO2018081530A1.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported