PROTAC-O4I2
CAT:
804-HY-141881-02
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PROTAC-O4I2
- CAS Number: 2785323-62-6
- UNSPSC Description: PROTAC-O4I2 is a PROTAC targets splicing factor 3B1 (SF3B1). PROTAC-O4I2 induces FLAG-SF3B1 degradation with an IC50 value of 0.244 μM in K562 cells. PROTAC-O4I2 also induces cellular apoptosis in K562 WT cells[1].
- Target Antigen: Apoptosis; PROTACs; SF3B1
- Type: Reference compound
- Related Pathways: Apoptosis;Epigenetics;PROTAC
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/protac-o4i2.html
- Solubility: DMSO : 250 mg/mL (ultrasonic)
- Smiles: O=C(NCCCCCCNC1=CC=CC2=C1C(N(C2=O)C3CCC(NC3=O)=O)=O)C4=CSC(NC5=CC=C(C=C5)Cl)=N4
- Molecular Weight: 609.10
- References & Citations: [1]Rodrigo A Gama-Brambila, et al. A PROTAC targets splicing factor 3B1. Cell Chem Biol. 2021 Nov 18;28(11):1616-1627.e8.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported