O4I2

• Description :

  O4I2 is a potent Oct3/4 inducer. O4I2 induces the expression of pluripotent-associated genes Lin28, Sox2 and Nanog, and suppresses Rex1[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H312, H315, H319, H332, H335

• Target :

  Oct3/4

• Type :

  Reference compound

• Related Pathways :

  Stem Cell/Wnt

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/O4I2.html

• Concentration :

  10mM

• Purity :

  99.18

• Solubility :

  DMSO : ≥ 42 mg/mL

• Smiles :

  O=C(C1=CSC(NC2=CC=C(Cl)C=C2)=N1)OCC

• Molecular Formula :

  C12H11ClN2O2S

• Molecular Weight :

  282.75

• Precautions :

  H302, H312, H315, H319, H332, H335

• References & Citations :

  [1]Cheng X, et al. Ethyl 2- ((4-Chlorophenyl) amino) thiazole-4-carboxylate and Derivatives Are Potent Inducers of Oct3/4. J Med Chem. 2015 Aug 13;58 (15) :5742-5750.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [165682-93-9]