DALDA (TFA)

CAT: 0804-HY-P3870BSize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-P3870BSize:1 Each
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Description
DALDA TFA is a potent and highly selective μ-opioid receptor agonist with a Ki of 1.69 nM. DALDA TFA shows antinociceptive and respiratory effects[1].
UNSPSC
12352209
Target
Opioid Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dalda-tfa.html
Solubility
10 mM in DMSO
Smiles
OC(C=C1)=CC=C1C[C@H](N)C(N[C@H](CCCNC(N)=N)C(N[C@H](C(N[C@H](C(N)=O)CCCCN)=O)CC2=CC=CC=C2)=O)=O.OC(C(F)(F)F)=O.[x]
Molecular Formula
C30H45N9O5.xC2HF3O2
Molecular Weight
611.74 (free base)
References & Citations
[1]Shimoyama M, et al. Antinociceptive and respiratory effects of intrathecal H-Tyr-D-Arg-Phe-Lys-NH2 (DALDA) and [Dmt1] DALDA. Journal of Pharmacology and Experimental Therapeutics, 2001, 297 (1) : 364-371.|[2]Meyer ME, et al. DALDA (H-Tyr-D-Arg-Phe-Lys-NH2), a potent mu-opioid peptide agonist, affects various patterns of locomotor activities. Pharmacol Biochem Behav. 1995 May;51 (1) :149-51.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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