DALDA (TFA)

• Description:

  DALDA TFA is a potent and highly selective μ-opioid receptor agonist with a Ki of 1.69 nM. DALDA TFA shows antinociceptive and respiratory effects[1].

• UNSPSC:

  12352209

• Target:

  Opioid Receptor

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/dalda-tfa.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC(C=C1)=CC=C1C[C@H](N)C(N[C@H](CCCNC(N)=N)C(N[C@H](C(N[C@H](C(N)=O)CCCCN)=O)CC2=CC=CC=C2)=O)=O.OC(C(F)(F)F)=O.[x]

• Molecular Formula:

  C30H45N9O5.xC2HF3O2

• Molecular Weight:

  611.74 (free base)

• References & Citations:

  [1]Shimoyama M, et al. Antinociceptive and respiratory effects of intrathecal H-Tyr-D-Arg-Phe-Lys-NH2 (DALDA) and [Dmt1] DALDA. Journal of Pharmacology and Experimental Therapeutics, 2001, 297 (1) : 364-371.|[2]Meyer ME, et al. DALDA (H-Tyr-D-Arg-Phe-Lys-NH2), a potent mu-opioid peptide agonist, affects various patterns of locomotor activities. Pharmacol Biochem Behav. 1995 May;51 (1) :149-51.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported