Smad2/3-IN-2
CAT:
804-HY-162404
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Smad2/3-IN-2
- UNSPSC Description: Smad2/3-IN-2 (Compound 3) is an inhibitor for TGF-β-dependent Smad2/3 and IL-4-dependent STAT6 signaling pathway, with IC50s of 90 and 20 nM, respectively[1].
- Target Antigen: Interleukin Related; STAT; TGF-beta/Smad
- Type: Reference compound
- Related Pathways: Immunology/Inflammation;JAK/STAT Signaling;Stem Cell/Wnt;TGF-beta/Smad
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/smad2-3-in-2.html
- Solubility: 10 mM in DMSO
- Smiles: OC1=C(C(/C(C)=C/CC[C@H](C)[C@@H](C)OC2=O)=O)C(C2)=C(Cl)C(O)=C1
- Molecular Weight: 352.81
- References & Citations: [1]Seipp K, et al., Total Synthesis, Structure Reassignment, and Biological Evaluation of the Anti-Inflammatory Macrolactone 13-Hydroxy-14-deoxyoxacyclododecindione. J Nat Prod. 2024 Mar 31.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported