ApoER2 Recombinant Rabbit Monoclonal Antibody [JE31-73]

ApoER2 Recombinant Rabbit Monoclonal Antibody [JE31-73]

• Description: Low-density lipoprotein receptor-related protein 8 (LRP8), also known as apolipoprotein E receptor 2 (ApoER2), is a protein that in humans is encoded by the LRP8 gene. ApoER2 is a cell surface receptor that is part of the low-density lipoprotein receptor family. These receptors function in signal transduction and endocytosis of specific ligands. Through interactions with one of its ligands, reelin, ApoER2 plays an important role in embryonic neuronal migration and postnatal long-term potentiation. Another LDL family receptor, VLDLR, also interacts with reelin, and together these two receptors influence brain development and function. Decreased expression of ApoER2 is associated with certain neurological diseases.
• Product Name Alternative: APOER2 antibody Apolipoprotein E receptor 2 antibody low density lipoprotein receptor-related protein 8 antibody Low-density lipoprotein receptor-related protein 8 antibody LRP-8 antibody LRP8 antibody LRP8_HUMAN antibody
• Abbreviation: LRP8, APOER2
• CAS Number: 9000-83-3
• Swiss Prot: Q14114 Human, Q924X6 Mouse,
• Cellular Locus: Cell membrane, Secreted.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within Human ApoER2 aa 864-963 / 963.
• Isotype: IgG
• Clone: JE31-73
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P
• Positive Control: SH-SY5Y cell lysate, A549 cell lysate, U-87 MG cell lysate, HepG2 cell lysate, RAW264.7 cell lysate, C6 cell lysate, human testis tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IHC-P: 1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 106 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes