Gboxin

Gboxin

• CAS Number: 2101315-36-8
• UNSPSC Description: Gboxin is an oxidative phosphorylation (OXPHOS) inhibitor that targets glioblastoma. Gboxin inhibits the activity of F0F1 ATP synthase. Antitumour activity[1].
• Target Antigen: ATP Synthase; Mitochondrial Metabolism; Oxidative Phosphorylation
• Type: Reference compound
• Related Pathways: Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/Gboxin.html
• Purity: 98.23
• Solubility: DMSO : 32.5 mg/mL (ultrasonic)|H2O : 10 mg/mL (ultrasonic)
• Smiles: O=C(O[C@H]1[C@H](C(C)C)CC[C@@H](C)C1)CN2C(CC)=[N+](C)C3=CC=CC=C23.[Cl-]
• Molecular Weight: 392.96
• References & Citations: [1]Shi Y, et al. Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma. Nature. 2019 Mar;567(7748):341-346.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported