m-PEG3-CH2CH2COOH

• UNSPSC Description:

  m-PEG3-CH2CH2COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG3-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

• Target Antigen:

  ADC Linker; PROTAC Linkers

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/m-peg3-ch2ch2cooh.html

• Purity:

  97.0

• Solubility:

  10 mM in DMSO

• Smiles:

  COCCOCCOCCOCCC(O)=O

• Molecular Weight:

  236.26

• References & Citations:

  [1]Robert Lyon, et al. Pegylated drug-linkers for improved ligand-drug conjugate pharmacokinetics. WO2015057699A2.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  67319-28-2