Fmoc-NH-PEG3-CH2CH2COOH

• UNSPSC Description:

  Fmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG3-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• Target Antigen:

  ADC Linker; PROTAC Linkers

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/fmoc-nh-peg3-ch2ch2cooh.html

• Purity:

  99.80

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCOCCOCCOCCC(O)=O

• Molecular Weight:

  443.49

• References & Citations:

  [1]Kyoji TSUCHIKAMA, et al. Linkers for antibody drug conjugates. WO2018218004A1.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  867062-95-1