Carvedilol Glucuronide

• Description :

  Carvedilol Glucuronide is the metabolite of Carvedilol (HY-B0006) . Carvedilol (BM 14190) is an antagonist for β/α-1 adrenergic receptor. Carvedilol inhibits lipid peroxidation with an IC50 of 5 μM. Carvedilol is an antihypertensive agent with potential use in angina and congestive heart failure. Carvedilol is an autophagy inducer that inhibits the NLRP3 inflammasome[1].

• UNSPSC :

  12352005

• Target :

  Drug Metabolite

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Others; Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/carvedilol-glucuronide.html

• Smiles :

  OC([C@@H](O[C@H]1OC(COC2=C3C4=CC=CC=C4NC3=CC=C2)CNCCOC5=C(OC)C=CC=C5)[C@@H](O)[C@H](O)[C@H]1O)=O

• Molecular Formula :

  C30H34N2O10

• Molecular Weight :

  582.60

• References & Citations :

  [1]Hanioka N, et al., Stereoselective glucuronidation of carvedilol in human liver and intestinal microsomes. Pharmacology. 2012;90 (3-4) :117-24.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [114869-83-9]