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Candesartan (Standard)

CAT: 0804-HY-B0205R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0205R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Candesartan (Standard) is the analytical standard of Candesartan. This product is intended for research and analytical applications. Candesartan (CV 11974) is an orally active angiotensin II AT1-Receptor blocker and PPAR-γ agonist. Candesartan has potent and long-lasting antihypertensive effects. Candesartan can be used for the research of hypertension, chronic heart failure (CHF) and Traumatic brain injury (TBI) [1][2][3].
CAS Number
139481-59-7
Product Name Alternative
CV 11974 (Standard)
UNSPSC
12352005
Target
Angiotensin Receptor; PPAR; Reference Standards
Type
Reference Standards
Related Pathways
Cell Cycle/DNA Damage; GPCR/G Protein; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Cardiovascular Disease; Endocrinology; Cancer
Assay Protocol
https://www.medchemexpress.com/candesartan-standard.html
Purity
98.00
Smiles
O=C(C1=C2C(N=C(OCC)N2CC3=CC=C(C4=CC=CC=C4C5=NNN=N5)C=C3)=CC=C1)O
Molecular Formula
C24H20N6O3
Molecular Weight
440.45
References & Citations
[1]Pfeffer MA, et al. Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme. Lancet. 2003 Sep 6;362 (9386) :759-66.|[2]Nishimura Y, et al. Chronic peripheral administration of the angiotensin II AT (1) receptor antagonist candesartan blocks brain AT (1) receptors. Brain Res. 2000 Jul 14;871 (1) :29-38.|[3]Sonia Villapol, et al. Candesartan, an angiotensin II AT₁-receptor blocker and PPAR-γ agonist, reduces lesion volume and improves motor and memory function after traumatic brain injury in mice. Neuropsychopharmacology. 2012 Dec;37 (13) :2817-29.
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
Launched

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