Glutaminase-IN-3

• UNSPSC Description:

  Glutaminase-IN-3 (compound 657) is a potent glutaminase inhibitor with an IC50 of 0.24 μM for Glutaminase 1 (GLS1). Glutaminase-IN-3 is extracted from patent WO2014089048A1, compound 657[1].

• Target Antigen:

  Glutaminase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/glutaminase-in-3.html

• Purity:

  98.47

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=C(CC1=CC=CC(OC(F)(F)F)=C1)NC2=NN=C(CCCCC3=NN=C(N)S3)C=C2

• Molecular Weight:

  452.462

• References & Citations:

  [1]Mark K. Bennett, et al. Treatment of cancer with heterocyclic inhibitors of glutaminase. WO2014089048A1.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  1439399-45-7