PERK-IN-2
CAT:
804-HY-135220-03
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PERK-IN-2
- CAS Number: 1337531-83-5
- UNSPSC Description: PERK-IN-2 is a potent PERK inhibitor with an IC50 of 0.2 nM[1].
- Target Antigen: PERK
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/perk-in-2.html
- Smiles: FC1=CC(F)=C(F)C(CC(N2CCC3=C2C=CC(C4=CN(C)C5=NC=NC(N)=C54)=C3)=O)=C1
- Molecular Weight: 437.42
- References & Citations: [1]Axten JM , et al. Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK). J Med Chem. 2012 Aug 23;55(16):7193-207.
- Shipping Conditions: Room Temperature