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PF-3635659

CAT: 0804-HY-15502-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-15502-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF-3635659 is a potent antagonist of the muscarinic M3 receptor (mAChR3) . PF-3635659 can be used for chronic obstructive pulmonary disease (COPD) research[1].
CAS Number
931409-24-4
UNSPSC
12352005
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pf-3635659.html
Solubility
10 mM in DMSO
Smiles
O=C(C(C1=CC=CC=C1)(CCC(C)(C)N2CC(C2)OC3=CC(O)=CC=C3)C4=CC=CC=C4)N
Molecular Formula
C28H32N2O3
Molecular Weight
444.57
References & Citations
[1]Dillon B R, et al.Development of a Scaleable Synthesis of a Geminal Dimethyl Tertiary Amine as an Inhaled Muscarinic Antagonist for the Treatment of COPD[J].Organic Process Research & Development, 2012, 16 (2) :195-203.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAChR3

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