HQ-415

• UNSPSC Description:

  HQ-415 is a biologically active metal chelator related to Clioquinol, with an EC50 of 15 μM.

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/HQ-415.html

• Purity:

  98.10

• Solubility:

  DMSO : 5.6 mg/mL (ultrasonic;warming)

• Smiles:

  OC1=C2N=CC=CC2=CC=C1C(C3=CC=C(OC)C(OCC)=C3)NC4=NC=CC(C)=C4

• Molecular Weight:

  415.48

• References & Citations:

  [1]Tardiff DF, et al. Different 8-hydroxyquinolines protect models of TDP-43 protein, α-synuclein, and polyglutamine proteotoxicity through distinct mechanisms. J Biol Chem. 2012 Feb 3;287(6):4107-4120.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  430462-93-4