LBM-415

• Description:

  LBM-415 (NVP-PDF 713) is a peptide deformylase (PDF) inhibitor that exhibits inhibitory activity against various antimicrobial-resistant gram-positive cocci, with a MIC90 range of 0.12-8 µg/ml. Additionally, inhibiting efflux pump activity can enhance bacterial sensitivity to LBM415, thereby improving its antibacterial efficacy[1].

• Product Name Alternative:

  NVP-PDF 713; VIC-104959

• UNSPSC:

  12352005

• Target:

  Antibiotic; Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/lbm-415.html

• Smiles:

  O=C ([C@H]1N (C ([C@@H] (CN (C=O) O) CCCC) =O) CCC1) NC2=CC=C (F) C=[N+]2[O-]

• Molecular Formula:

  C18H25FN4O5

• Molecular Weight:

  396.41

• References & Citations:

  [1]Fritsche TR, et al. Comparative antimicrobial characterization of LBM415 (NVP PDF-713), a new peptide deformylase inhibitor of clinical importance. Antimicrob Agents Chemother. 2005 Apr;49 (4) :1468-76.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  478913-91-6