Ac-macropa

• Description:

  Ac-macropa is a PSMA-targeted Actinium-225 Conjugate, and can be used for study of prostate cancer[1].

• UNSPSC:

  12352005

• Target:

  PSMA

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ac-macropa.html

• Smiles:

  S=C(NC1=CC=C(CCOC2=CC3=[N]C(C[N@@]45[Ac]([O](CC6)CC7)([O](CC8)CC9)([O]8CC4)([O]6CC5)([O]C%10=O)([O]C3=O)[N@]79CC%11=CC=CC%10=[N]%11)=C2)C=C1)NCCCC

• Molecular Formula:

  C39H52AcN6O9S

• Molecular Weight:

  1007.93

• References & Citations:

  [1]Schatz CA, Moen I, et al. Preclinical Efficacy of a PSMA-Targeted Actinium-225 Conjugate (225Ac-Macropa-Pelgifatamab) : A Targeted Alpha Therapy for Prostate Cancer. Clin Cancer Res. 2024;30 (11) :2531-2544.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported