CENP-E-IN-3

• Description :

  CENP-E-IN-3 (compound 4) is a potent CENP-E inhibitor. CENP-E-IN-3 has the potential for the research of cancer[1].

• UNSPSC :

  12352005

• Target :

  Kinesin

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; Cytoskeleton

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/cenp-e-in-3.html

• Smiles :

  ClC1=C(OC(C)C)C=CC(C(N[C@H](C(NC)=O)CC2=CC=C(/N=N/C3=C(C)N(C(N)=O)N=C3C)C=C2)=O)=C1

• Molecular Formula :

  C26H30ClN7O4

• Molecular Weight :

  540.01

• References & Citations :

  [1]Matsuo K, et al. A chemical platform for the efficient screening of arylazopyrazole-based photoswitchable CENP-E inhibitors using mild cyclization reactions. Bioorg Med Chem Lett. 2024 Jul 17;111:129892.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Kinesin-7/CENP-E