CENP-E-IN-3

• Description:

  CENP-E-IN-3 (compound 4) is a potent CENP-E inhibitor. CENP-E-IN-3 has the potential for the research of cancer[1].

• UNSPSC:

  12352005

• Target:

  Kinesin

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage; Cytoskeleton

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cenp-e-in-3.html

• Smiles:

  ClC1=C(OC(C)C)C=CC(C(N[C@H](C(NC)=O)CC2=CC=C(/N=N/C3=C(C)N(C(N)=O)N=C3C)C=C2)=O)=C1

• Molecular Formula:

  C26H30ClN7O4

• Molecular Weight:

  540.01

• References & Citations:

  [1]Matsuo K, et al. A chemical platform for the efficient screening of arylazopyrazole-based photoswitchable CENP-E inhibitors using mild cyclization reactions. Bioorg Med Chem Lett. 2024 Jul 17;111:129892.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Kinesin-7/CENP-E