Milrinone (Standard)

• Description:

  Milrinone (Standard) is the analytical standard of Milrinone. This product is intended for research and analytical applications. Milrinone is a PDE3 inhibitor, and also an inotrope and vasodilator.

• Product Name Alternative:

  Win 47203 (Standard)

• UNSPSC:

  12352005

• Target:

  Phosphodiesterase (PDE) ; Reference Standards

• Type:

  Reference Standards

• Related Pathways:

  Metabolic Enzyme/Protease; Others

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/milrinone-standard.html

• Smiles:

  CC(N1)=C(C2=CC=NC=C2)C=C(C#N)C1=O

• Molecular Formula:

  C12H9N3O

• Molecular Weight:

  211.22

• References & Citations:

  [1]Santhosh KT, et al. Milrinone attenuates thromboxane receptor-mediated hyperresponsiveness in hypoxic pulmonary arterial myocytes. Br J Pharmacol. 2011 Jul;163 (6) :1223-36.|[2]Hentschel T, et al. Inhalation of the phosphodiesterase-3 inhibitor milrinone attenuates pulmonary hypertension in a rat model of congestive heart failure. Anesthesiology. 2007 Jan;106 (1) :124-31.|[3]Kishi T, et al. Effects of milrinone on left ventricular end-systolic pressure-volume relationship of rat hearts in situ. Clin Exp Pharmacol Physiol. 2001 Sep;28 (9) :737-42.|[4]Taylor MS, et al. Effect of milrinone on small mesenteric artery vasoconstriction: role of K (+) channels. Am J Physiol. 1999 Jul;277 (1 Pt 1) :G69-78.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  [78415-72-2]