Geraniol

• Description:

  Geraniol is an olefin terpene with oral activity. Geraniol inhibits cell proliferation and promotes apoptosis. Geraniol has antibacterial, antifungal, antioxidant, anti-inflammatory and antitumor activities. Geraniol can be used to study diabetes[1][2][3][4][5].

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Apoptosis; Bacterial; Endogenous Metabolite; Fungal

• Type:

  Natural Products

• Related Pathways:

  Anti-infection; Apoptosis; Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Infection; Metabolic Disease; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/geraniol.html

• Purity:

  99.79

• Solubility:

  H2O : 1 mg/mL (ultrasonic; warming; heat to 80°C)

• Smiles:

  C/C(C)=C\CC/C(C)=C/CO

• Molecular Formula:

  C10H18O

• Molecular Weight:

  154.25

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Bard M, et al. Geraniol interferes with membrane functions in strains of Candida and Saccharomyces. Lipids. 1988 Jun;23 (6) :534-8.|[2]Kim SH, et al. Geraniol inhibits prostate cancer growth by targeting cell cycle and apoptosis pathways. Biochem Biophys Res Commun. 2011 Apr 1;407 (1) :129-34.|[3]Babukumar S, et al. Geraniol, a natural monoterpene, ameliorates hyperglycemia by attenuating the key enzymes of carbohydrate metabolism in streptozotocin-induced diabetic rats. Pharm Biol. 2017 Dec;55 (1) :1442-1449.|[4]Hosseini SM, et al. Geraniol attenuates oxidative stress, bioaccumulation, serological and histopathological changes during aluminum chloride-hepatopancreatic toxicity in male Wistar rats. Environ Sci Pollut Res Int. 2020 Jun;27 (16) :20076-20089.|[5]Pereira Fde O, et al. Antifungal activity of geraniol and citronellol, two monoterpenes alcohols, against Trichophyton rubrum involves inhibition of ergosterol biosynthesis. Pharm Biol. 2015 Feb;53 (2) :228-34.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [106-24-1]