Geranial

CAT: 0804-HY-W1000105-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0804-HY-W1000105-01Size:25 mg
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Description
Geranial ((E) -3,7-Dimethylocta-2,6-dienal) is a derivative of geraniol with anti-inflammatory activity. Geranial can inhibit the secretion of TNF-α and IL-6 in macrophages. Furthermore, Geranial also inhibits the secretion of IL-1β mediated by the NLRP-3 inflammasome[1][2].
CAS Number
[141-27-5]
Product Name Alternative
(E) -3,7-Dimethylocta-2,6-dienal
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
Interleukin Related; NOD-like Receptor (NLR) ; TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/geranial.html
Purity
99.51
Smiles
C/C(C)=C\CC/C(C)=C/C=O
Molecular Formula
C10H16O
Molecular Weight
152.23
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Iijima Y, et al. Biosynthesis of geranial, a potent aroma compound in ginger rhizome (Zingiber officinale) : molecular cloning and characterization of geraniol dehydrogenase[J]. Plant Biotechnology, 2014, 31 (5) : 525-534.|[2]Liao P C, et al. Anti-inflammatory activity of neral and geranial isolated from fruits of Litsea cubeba Lour[J]. Journal of Functional Foods, 2015, 19: 248-258.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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