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Biotin-PEG3-aldehyde

CAT: 0804-HY-136051-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-136051-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Biotin-PEG3-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
CAS Number
889443-90-7
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/biotin-peg3-aldehyde.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
O=C1N[C@H]2[C@H](CS[C@H]2CCCCC(NCCOCCOCCOCCNC(C3=CC=C(C([H])=O)C=C3)=O)=O)N1
Molecular Formula
C26H38N4O7S
Molecular Weight
550.67
Precautions
H302, H315, H319, H335
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker

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