Products for Research Use Only
RegisterLogin

GSK163090

CAT: 0804-HY-14348-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-14348-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
GSK163090 is a potent, selective and orally active 5-HT1A/1B/1D receptor antagonist with pKi values of 9.4, 8.5 and 9.7, respectively. GSK163090 inhibits the functional activity of serotonin reuptake transporter (SerT) with a pKi value of 6.1. GSK163090 has antidepressant and anxiolytic activities[1].
CAS Number
844903-58-8
UNSPSC
12352005
Hazard Statement
H301
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/GSK163090.html
Concentration
10mM
Purity
99.57
Solubility
DMSO : 14.29 mg/mL (ultrasonic)
Smiles
O=C1NCCN1C2=CC=CC(CCN3CCN(C4=C5C=CC(C)=NC5=CC=C4)CC3)=C2
Molecular Formula
C25H29N5O
Molecular Weight
415.53
Precautions
H301
References & Citations
[1]Leslie CP, et al. Discovery of 1- (3-{2-[4- (2-methyl-5-quinolinyl) -1-piperazinyl]ethyl}phenyl) -2-imidazolidinone (GSK163090), a Potent, selective, and orally active 5-HT1A/B/D receptor antagonist. J Med Chem. 2010 Dec 9;53 (23) :8228-8240.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
5-HT1 Receptor

Alternative Products

CatalogName
522672GSK163090
A15838-10GSK163090 10mg
A15838-5GSK163090 5mg
A15838-25GSK163090 25mg
A15838-2GSK163090 2mg
A15838-100GSK163090 100mg
A15838-50GSK163090 50mg
A15838-1GSK163090 1mg
A15838-10mM-DGSK163090 10mM * 1mL in DMSO
MBS131437GSK163090 (GSK-163090; GSK 163090)

Popular Products