SDF-1α (human) (TFA)

• UNSPSC Description:

  SDF-1α (human) TFA is a mononuclear cells chemoattractant that can bind to CXCR4. SDF-1α plays a central role in stem cell homing, retention, survival, proliferation, cardiomyocyte repair, angiogenesis and ventricular remodelling following myocardial infarction. SDF-1α (human) TFA can be used in cardiovascular disease research[1][2].

• Target Antigen:

  CXCR

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein;Immunology/Inflammation

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/sdf-1α-human-tfa.html

• Smiles:

  O=C([C@@H](N)CCCCN)N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NC(C(N2C(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N3[C@H](C(N[C@H]4CC(N)=O)=O)CCC3)=O)[C@@H](C)O)=O)CC(N)=O)=O)CC(C)C)=O)[C@H](CC)C)=O)CCCCN)=O)CC(C)C)=O)CC5=CNC=N5)=O)CCCCN)=O)C(C)C)=O)CC(N)=O)=O)C)=O)CCCNC(N)=N)=O)C)=O)C(C)C)=O)CC6=CNC=N6)=O)CO)=O)CCC(O)=O)=O)CC7=CC=CC=C7)=O)CC8=CC=CC=C8)=O)CCCNC(N)=N)=O)CSSC[C@H](NC9=O)C(N[C@H](C(N[C@H](C(N%10[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CCCCN)=O)CC(N)=O)=O)CC(C)C)=O)C)=O)CCCCN)=O)CCC(O)=O)=O)CC(C)C)=O)CC%11=CC=C(O)C=C%11)=O)CCC(O)=O)=O)CCC(N)=O)=O)[C@H](CC)C)=O)CC%12=CNC%13=CC=CC=C%12%13)=O)CCCCN)=O)CC(C)C)=O)CCCCN)=O)CCC%10)=O)CC(O)=O)=O)[C@H](CC)C)=O)=O)CCC2)=O)CSSC[C@H](NC4=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]9C(C)C)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)CC(N)=O)=O)CC(N)=O)=O)CC(N)=O)=O)CCCCN)=O)CC(C)C)=O)CCCNC(N)=N)=O)C)=O)C(C)C)=O)[C@H](CC)C)=O)CCC(N)=O)=O)CC(C)C)=O)C)=O)=O)CCCNC(N)=N)=O)CC%14=CC=C(O)C=C%14)=O)CO)=O)CC(C)C)=O)CO)=O)C(C)C)=O)CCC1.O=C(O)C(F)(F)F.[x]

• Molecular Weight:

  7959.34 (free acid)

• References & Citations:

  [1]Gupta SK, et al. Modulation of CXCR4 expression and SDF-1alpha functional activity during differentiation of human monocytes and macrophages. J Leukoc Biol. 1999 Jul;66(1):135-43. |[2]Bromage DI, et al. Stromal derived factor 1α: a chemokine that delivers a two-pronged defence of the myocardium. Pharmacol Ther. 2014 Sep;143(3):305-15.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported