Abiraterone metabolite 1

• UNSPSC Description:

  Abiraterone metabolite 1 is a 5β-reduced metabolite of abiraterone. Abiraterone, a steroidal agent, inhibits CYP17A1, blocks androgen synthesis and prolongs survival in prostate cancer.

• Target Antigen:

  Drug Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Abiraterone_metabolite_1.html

• Purity:

  99.59

• Solubility:

  DMSO : ≥ 25 mg/mL

• Smiles:

  C[C@@]12C(C3=CN=CC=C3)=CC[C@]1([C@@]4(CC[C@@]5([H])[C@@](C)([C@]4(CC2)[H])CC[C@@H](C5)O)[H])[H]

• Molecular Weight:

  351.534

• References & Citations:

  [1]Li Z, et al. Redirecting abiraterone metabolism to fine-tune prostate cancer anti-androgen therapy. Nature. 2016 May 26;533(7604):547-51.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1940176-03-3