Margatoxin (TFA)

CAT: 0804-HY-P1280ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-P1280ASize:1 Each
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Description
Margatoxin TFA, an alpha-KTx scorpion toxin, is a high affinity inhibitor of Kv1.3 (Kd=11.7 pM) . Margatoxin TFA inhibits the Kv1.2 (Kd=6.4 pM) and Kv1.1 (Kd=4.2 nM) . Margatoxin TFA, a 39 amino-acid-long peptide, is isolated from the venom of the scorpion Centruroides margaritatus and widely used in ion channel research[1][2].
UNSPSC
12352209
Target
Potassium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/margatoxin-tfa.html
Solubility
10 mM in DMSO
Smiles
[TIINVKCTSPKQCLPPCKAQFGQSAGAKCMNGKCKCYPH(Disulfidebridge:Cys7-Cys29;Cys13-Cys34;Cys17-Cys36)(TFAsalt)]
Molecular Formula
C178H286N52O50S7.xC2HF3O2
Molecular Weight
4178.95 (free base)
References & Citations
+
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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