Margatoxin

CAT: 0804-HY-P1280-01Size: 100 µgDry Ice: NoHazardous: No
CAT#:0804-HY-P1280-01Size:100 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Margatoxin, an alpha-KTx scorpion toxin, is a high affinity inhibitor of Kv1.3 (Kd=11.7 pM) . Margatoxin inhibits the Kv1.2 (Kd=6.4 pM) and Kv1.1 (Kd=4.2 nM) . Margatoxin, a 39 amino-acid-long peptide, is isolated from the venom of the scorpion Centruroides margaritatus and widely used in ion channel research[1][2].
CAS Number
[145808-47-5]
UNSPSC
12352209
Hazard Statement
H302, H312, H332
Target
Potassium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/margatoxin.html
Purity
98.44
Solubility
DMSO : ≥ 2 mg/mL
Smiles
O=C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(N)=O)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC1=CC=CC=C1)C(NCC(N[C@@H](CCC(N)=O)C(N[C@@H](CO)C(N[C@@H](C)C(NCC(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CC2=CC=C(C=C2)O)C(N3[C@@H](CCC3)C(N[C@@H](CC4=CNC=N4)C(O)=O)=O)=O)=O)NC5=O)C(N[C@@H](CCSC)C(N[C@@H](CC(N)=O)C(NCC(N[C@H]6CCCCN)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC7=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CO)C(N8[C@@H](CCC8)C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(N[C@@H](CSSC[C@@H](C(N[C@H]5CCCCN)=O)NC6=O)C(N[C@@H](CC(C)C)C(N9[C@@H](CCC9)C(N%10[C@H]7CCC%10)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@H](O)C)N
Molecular Formula
C178H286N52O50S7
Molecular Weight
4178.95
Precautions
H302, H312, H332
References & Citations
+
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported

Related Products

CatalogName
HY-N10037Marginatoxin

Alternative Products

CatalogName
M30649-01Margatoxin
MBS5821693Margatoxin TFA
454200-01Margatoxin, Recombinant

Popular Products