BAY-850

• Description :

  BAY-850, a chemical probe, is a potent and isoform selective ATPase family AAA domain-containing protein 2 (ATAD2) inhibitor, with an IC50 of 166 nM[1].

• UNSPSC :

  12352005

• Target :

  Epigenetic Reader Domain

• Type :

  Reference compound

• Related Pathways :

  Epigenetics

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/BAY-850.html

• Purity :

  98.33

• Solubility :

  DMSO : 62.5 mg/mL (ultrasonic)

• Smiles :

  O=C(N[C@H](CC1=CC=C(C#N)C=C1)CN[C@H]2CC[C@@H](N)CC2)C3=CC(C4=CC=C(CN[C@@H](C5=CC=C(C)C=C5)C)O4)=C(OC)C=C3Cl

• Molecular Formula :

  C38H44ClN5O3

• Molecular Weight :

  654.24

• References & Citations :

  [1]Fernández-Montalván AE, et al. Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action. ACS Chem Biol. 2017 Nov 17;12 (11) :2730-2736.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2099142-76-2]