3-Hydroxybenzaldehyde

CAT: 0804-HY-76006-01Size: 25 gDry Ice: NoHazardous: No
CAT#:0804-HY-76006-01Size:25 g
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Description
3-Hydroxybenzaldehyde (3-HBA) is a precursor compound for phenolic compounds like Protocatechuic aldehyde (PCA) (HY-N0295) . 3-Hydroxybenzaldehyde, produced by 3-hydroxybenzyl-alcohol dehydrogenase, is a substrate of aldehyde dehydrogenase (ALDH) in rats and humans. 3-Hydroxybenzaldehyde has vasculoprotective effects in vitro and in vivo. 3-Hydroxybenzaldehyde is proming for research of atherosclerosis[1][2][3][4].
CAS Number
[100-83-4]
Product Name Alternative
M-Hydroxybenzaldehyde
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Aldehyde Dehydrogenase (ALDH) ; NF-κB; p38 MAPK
Type
Natural Products
Related Pathways
MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/3-hydroxybenzaldehyde.html
Purity
99.89
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=CC1=CC=CC(O)=C1
Molecular Formula
C7H6O2
Molecular Weight
122.12
Precautions
H315, H319
References & Citations
[1]Kong BS, et al. Vasculoprotective Effects of 3-Hydroxybenzaldehyde against VSMCs Proliferation and ECs Inflammation.PLoS One. 2016 Mar 22;11 (3) :e0149394.|[2]Paixão JA, et al. 3-Hydroxybenzaldehyde. Acta Crystallogr C. 2000 Nov;56 Pt 11:1348-50. |[3]Chen K Y, et al. Protective effect of benzaldehyde combined with albendazole against brain injury induced by Angiostrongylus cantonensis infection in mice[J]. International Journal of Antimicrobial Agents, 2023, 62 (5) : 106963.|[4]Muthu S, et al. Quantum chemical studies, vibrational analysis, molecular structure, first order hyper polarizability, NBO and HOMO-LUMO analysis of 3-hydroxybenzaldehyde and its cation[J]. Spectrochim Acta A Mol Biomol Spectrosc. 2013 Nov;115:789-99.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
ALDH2

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