3-Hydroxybenzaldehyde

• UNSPSC Description:

  3-Hydroxybenzaldehyde (3-HBA) is a precursor compound for phenolic compounds like Protocatechuic aldehyde (PCA) (HY-N0295). 3-Hydroxybenzaldehyde, produced by 3-hydroxybenzyl-alcohol dehydrogenase, is a substrate of aldehyde dehydrogenase (ALDH) in rats and humans. 3-Hydroxybenzaldehyde has vasculoprotective effects in vitro and in vivo. 3-Hydroxybenzaldehyde is proming for research of atherosclerosis[1][2][3][4].

• Target Antigen:

  Aldehyde Dehydrogenase (ALDH); NF-κB; p38 MAPK

• Type:

  Natural Products

• Related Pathways:

  MAPK/ERK Pathway;Metabolic Enzyme/Protease;NF-κB

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/3-hydroxybenzaldehyde.html

• Purity:

  99.87

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=CC1=CC=CC(O)=C1

• Molecular Weight:

  122.123

• References & Citations:

  [1]Kong BS, et al. Vasculoprotective Effects of 3-Hydroxybenzaldehyde against VSMCs Proliferation and ECs Inflammation.PLoS One. 2016 Mar 22;11(3):e0149394.|[2]Paixão JA, et al. 3-Hydroxybenzaldehyde. Acta Crystallogr C. 2000 Nov;56 Pt 11:1348-50. |[3]Chen K Y, et al. Protective effect of benzaldehyde combined with albendazole against brain injury induced by Angiostrongylus cantonensis infection in mice[J]. International Journal of Antimicrobial Agents, 2023, 62(5): 106963.|[4]Muthu S, et al. Quantum chemical studies, vibrational analysis, molecular structure, first order hyper polarizability, NBO and HOMO-LUMO analysis of 3-hydroxybenzaldehyde and its cation[J]. Spectrochim Acta A Mol Biomol Spectrosc. 2013 Nov;115:789-99.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, stored under nitrogen)

• Clinical Information:

  No Development Reported

• CAS Number:

  100-83-4