P-Hydroxybenzaldehyde-d5

• Description :

  P-Hydroxybenzaldehyde-d5 is the deuterium labeled p-Hydroxybenzaldehyde[1]. p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations[2].

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  Endogenous Metabolite; GABA Receptor

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C([2H])C1=C([2H])C([2H])=C(C([2H])=C1[2H])O

• Molecular Formula :

  C7HD5O2

• Molecular Weight :

  127.15

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Zhang J, et al. The Effect of 4-hydroxybenzaldehyde on the γ-aminobutyric Acid Type A Receptor. Malays J Med Sci. 2017 Mar;24 (2) :94-99.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported

• CAS Number :

  [298704-22-0]