CJ-13,610 (hydrochloride)
CAT:
804-HY-106200A
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CJ-13,610 (hydrochloride)
- CAS Number: 179420-27-0
- UNSPSC Description: CJ-13,610 (hydrochloride) is an orally active and potent nonredox-type 5-lipoxygenase inhibitor with an IC50 value of 0.07 μM. CJ-13,610 (hydrochloride) competes with activating LOOH at a regulatory LOOH-binding site with high affinity, thereby preventing 5-lipoxygenase catalysis. CJ-13,610 (hydrochloride) is promising for research of diseases related to elevated levels of 5-lipoxygenase such as inflammatory reactions, allergic asthma, various types of cancer and atherosclerosis[1].
- Target Antigen: Lipoxygenase
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Field of Research: Cancer; Inflammation/Immunology; Cardiovascular Disease
- Assay Protocol: https://www.medchemexpress.com/cj-13-610-hydrochloride.html
- Smiles: NC(C1(C2=CC(SC3=CC=C(N4C(C)=NC=C4)C=C3)=CC=C2)CCOCC1)=O.Cl
- Molecular Weight: 429.96
- References & Citations: [1]Fischer L, et al. Molecular pharmacological profile of the nonredox-type 5-lipoxygenase inhibitor CJ-13,610. Br J Pharmacol. 2004 Jul;142(5):861-8.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported