Liraglutide

CAT: 0804-HY-P0014-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-P0014-01Size:1 mg
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Description
Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus.
CAS Number
[204656-20-2]
UNSPSC
12352209
Hazard Statement
H315, H319, H335
Target
GCGR; GLP Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Liraglutide.html
Purity
99.85
Solubility
0.1 M NaOH : 12.5 mg/mL (adjust pH to 8 with 0.1 M NaOH) |H2O : 9.52 mg/mL (adjust pH to 3 with 1 M HCl)
Smiles
[His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-{Lys(gGlu-C16acid)}-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly]
Molecular Formula
C172H265N43O51
Molecular Weight
3751.20
Precautions
H315, H319, H335
References & Citations
[1]Wang Y, et al. Transformation of oligomers of lipidated peptide induced by change in pH.Mol Pharm. 2015 Feb 2;12 (2) :411-9.|[2]Wang YG, et al. Liraglutide reduces oxidized LDL-induced oxidative stress and fatty degeneration in Raw 264.7 cells involving the AMPK/SREBP1 pathway.J Geriatr Cardiol. 2015 Jul;12 (4) :410-416.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
Launched

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