Bromoenol Lactone

Bromoenol Lactone_x000D_ Catalog number: B2014104_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 2.5 mg_x000D_ Molecular Weight or Concentration: 317.1 g/mol_x000D_ Supplied as: Powder_x000D_ Applications: molecular tool for various biochemical applications_x000D_ Storage: -20°C_x000D_ Keywords: BEL, E-6-(Bromoethylene)tetrahydro-3-(1-naphthyl)-2H-pyran-2-one_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Calderon LE, Liu S, Arnold N, Breakall B, Rollins J, Ndinguri M. Bromoenol Lactone Attenuates Nicotine-Induced Breast Cancer Cell Proliferation and Migration PLoS One. 2015 Nov 20;10(11):e0143277._x000D_ 2: Fernandes ACS, Soares DC, Neves RFC, Koeller CM, Heise N, Adade CM, Frases S, Meyer-Fernandes JR, Saraiva EM, Souto-Padr_n T. Endocytosis and Exocytosis in Leishmania amazonensis Are Modulated by Bromoenol Lactone Front Cell Infect Microbiol. 2020 Feb 7;10:39._x000D_ 3: Chakraborty S, Berwick ZC, Bartlett PJ, Kumar S, Thomas AP, Sturek M, Tune JD, Obukhov AG. Bromoenol lactone inhibits voltage-gated Ca2+ and transient receptor potential canonical channels J Pharmacol Exp Ther. 2011 Nov;339(2):329-40._x000D_ 4: Tsuchida K, Ibuki T, Matsumura K. Bromoenol Lactone, an Inhibitor of Calcium-Independent Phospholipase A2, Suppresses Carrageenan-Induced Prostaglandin Production and Hyperalgesia in Rat Hind Paw Mediators Inflamm. 2015;2015:605727._x000D_ 5: Chaib N, Kabr E, Alzola E, Pochet S, Dehaye JP. Bromoenol_lactone enhances the permeabilization of rat submandibular acinar cells by P2X7 agonists Br J Pharmacol. 2000 Feb;129(4):703-8._x000D_ 6: Balsinde J, Dennis EA. Bromoenol lactone inhibits magnesium-dependent phosphatidate phosphohydrolase and blocks triacylglycerol biosynthesis in mouse P388D1 macrophages J Biol Chem. 1996 Dec 13;271(50):31937-41._x000D_ 7: Fuentes L, Prez R, Nieto ML, Balsinde J, Balboa MA. Bromoenol_lactone promotes cell death by a mechanism involving phosphatidate phosphohydrolase-1 rather than calcium-independent phospholipase A2 J Biol Chem. 2003 Nov 7;278(45):44683-90._x000D_ 8: Fensome-Green A, Stannard N, Li M, Bolsover S, Cockcroft S. Bromoenol_lactone, an inhibitor of Group V1A calcium-independent phospholipase A2 inhibits antigen-stimulated mast cell exocytosis without blocking Ca2+ influx Cell Calcium. 2007 Feb;41(2):145-53._x000D_ 9: Song H, Ramanadham S, Bao S, Hsu FF, Turk J. A bromoenol_lactone suicide substrate inactivates group VIA phospholipase A2 by generating a diffusible bromomethyl keto acid that alkylates cysteine thiols Biochemistry. 2006 Jan 24;45(3):1061-73._x000D_ 10: Kurusu S, Matsui K, Watanabe T, Tsunou T, Kawaminami M. The cytotoxic effect of bromoenol lactone, a calcium-independent phospholipase A2 inhibitor, on rat cortical neurons in culture Cell Mol Neurobiol. 2008 Dec;28(8):1109-18. _x000D_ _x000D_ Products Related to Bromoenol Lactone can be found at Chemicals

Catalog Number: B2014104 (2.5 mg)

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