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Methionine

CAT: 0804-HY-13694-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0804-HY-13694-01Size:1 g
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Description
Methionine (MRX-1024; D-Methionine) is an effective chemoprotective agent which can also inhibit the neuronal activity through GABAA receptor activation.
CAS Number
348-67-4
Product Name Alternative
MRX-1024; D-Methionine
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/MRX-1024.html
Concentration
10mM
Purity
99.86
Solubility
H2O : 25 mg/mL (ultrasonic)
Smiles
N[C@H](CCSC)C(O)=O
Molecular Formula
C5H11NO2S
Molecular Weight
149.22
Precautions
H302, H315, H319, H335
References & Citations
[1]Wu C, et al. Antioxidants L-carnitine and D-methionine modulate neuronal activity through GABAergic inhibition. J Neural Transm (Vienna) . 2014 Jul;121 (7) :683-93.|[2]Sooriyaarachchi M, et al. Chemoprotection by D-methionine against cisplatin-induced side-effects: insight from in vitrostudies using human plasma. Metallomics. 2014 Mar;6 (3) :532-41.|[3]Hinduja S, et al. D-methionine protects against cisplatin-induced neurotoxicity in the hippocampus of the adult rat. Neurotox Res. 2015 Apr;27 (3) :199-204.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Human Endogenous Metabolite

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