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ATF4 antibody

CAT: 0710-FNab10416Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab10416Size:100 µg
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Background
The antibody recognizes the 38kd ATF4 protein and its phosphorylated forms (50kd) . ATF4 can bind DNA as a homodimer and as a heterodimer.
Synonyms
Cyclic AMP-dependent transcription factor ATF-4 (cAMP-dependent transcription factor ATF-4) |Activating transcription factor 4|Cyclic AMP-responsive element-binding protein 2 (CREB-2, cAMP-responsive element-binding protein 2) |Tax-responsive enhancer element-binding protein 67 (TaxREB67) |ATF4|CREB2|TXREB
Gene ID
468
UniProt
P18848
Host
Rabbit
Reactivity
Human
Immunogen
Activating transcription factor 4 (tax-responsive enhancer element B67)
Target
ATF4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Epigenetics, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50-58 kDa, 35-38 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
1-200aa

UniProtKB · P18848

Cyclic AMP-dependent transcription factor ATF-4

ATF4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P18848
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ATF4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
cAMP-dependent transcription factor ATF-4
EC number
—
Processing
—
Secondary accessions
Q96AQ3, Q9UH31
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationHydroxylationIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-bindingRepressor

Biological process

Biological rhythmsTranscriptionTranscription regulation

Cellular component

Cell membraneCytoplasmCytoskeletonMembraneNucleus

Domain

Coiled coil

Alternative Products