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S100A7 Rabbit pAb

CAT: 0855-ES13280-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES13280-01Size:50 µL
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Background
S100 calcium binding protein A7 (S100A7) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities. [provided by RefSeq, Nov 2014]
Description
S100 calcium binding protein A7 (S100A7) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities. [provided by RefSeq, Nov 2014],
Product Name Alternative
Protein S100-A7 (Psoriasin; S100 calcium-binding protein A7)
UniProt
P31151
Swiss Prot
P31151
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human S100A7 AA range: 1-51
Target
S100A7
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cytoplasm . Secreted . Secreted by a non-classical secretory pathway.
Other Product Names
Protein S100-A7 (Psoriasin; S100 calcium-binding protein A7)
Gene ID (Human)
6278

UniProtKB · P31151

Protein S100-A7

S10A7_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P31151
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
S100A7
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q5SY67, Q6FGE3, Q9H1E2
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationDisulfide bond

Ligand

CalciumMetal-bindingZinc

Cellular component

CytoplasmSecreted

Domain

Repeat

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