TCO-PEG4-NHS ester
CAT:
804-HY-141167A-03
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TCO-PEG4-NHS ester
- CAS Number: 1621096-79-4
- UNSPSC Description: TCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. TCO-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
- Target Antigen: PROTAC Linkers
- Type: Reference compound
- Related Pathways: PROTAC
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/e-tco-peg4-nhs-ester.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(OC1CC/C=C/CCC1)NCCOCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O
- Molecular Weight: 514.57
- References & Citations: [1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1013.
- Shipping Conditions: Blue Ice
- Clinical Information: No Development Reported