Gomisin E

• UNSPSC Description:

  Gomisin E, a dibenzocyclooctadiene lignan isolated from the fruits of Schizandra chinensis, inhibits NFAT transcription with an IC50 of 4.73 μM[1][2].

• Target Antigen:

  Nuclear Factor of activated T Cells (NFAT)

• Type:

  Natural Products

• Related Pathways:

  Immunology/Inflammation

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/gomisin-e.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=C(OC)C(OC)=CC2=C1C(C(C[C@H](C)[C@H](C)[C@H]2O3)=CC4=C5OCO4)=C5OC[C@@H](C)[C@](O)(C)C3=O

• Molecular Weight:

  514.56

• References & Citations:

  [1]YUKINOBU IKEYA, et al. The Constituents of Schizandra chinensis BAILL. V. The Structures of Four New Lignans, Gomisin N, Gomisin O, Epigomisin O and Gomisin E, and Transformation of Gomisin N to Deangeloylgomisin B.|[2]Im Seon Lee, et al. Lignans with Inhibitory Activity against NFAT Transcription from Schisandra chinensis.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  72960-21-5