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Gomisin E

CAT: 0804-HY-N7310-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N7310-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Gomisin E, a dibenzocyclooctadiene lignan isolated from the fruits of Schizandra chinensis, inhibits NFAT transcription with an IC50 of 4.73 μM[1][2].
CAS Number
72960-21-5
UNSPSC
12352005
Target
Nuclear Factor of activated T Cells (NFAT)
Type
Natural Products
Related Pathways
Immunology/Inflammation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/gomisin-e.html
Purity
96.0
Solubility
10 mM in DMSO
Smiles
COC1=C(OC)C(OC)=CC2=C1C(C(C[C@H](C)[C@H](C)[C@H]2O3)=CC4=C5OCO4)=C5OC[C@@H](C)[C@](O)(C)C3=O
Molecular Formula
C28H34O9
Molecular Weight
514.56
References & Citations
[1]YUKINOBU IKEYA, et al. The Constituents of Schizandra chinensis BAILL. V. The Structures of Four New Lignans, Gomisin N, Gomisin O, Epigomisin O and Gomisin E, and Transformation of Gomisin N to Deangeloylgomisin B.|[2]Im Seon Lee, et al. Lignans with Inhibitory Activity against NFAT Transcription from Schisandra chinensis.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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