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LRC3B rabbit pAb

CAT: 0855-ES15120-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES15120-01Size:50 µL
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Background
The protein encoded by this gene is a tumor suppressor, with lowered expression levels found in gastric, renal, colorectal, lung, and breast cancer tissues. The promoter of this gene is frequently hypermethylated in these cancer tissues, although the hypermethylation does not appear to be the cause of the reduced expression of this gene. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015]
Description
The protein encoded by this gene is a tumor suppressor, with lowered expression levels found in gastric, renal, colorectal, lung, and breast cancer tissues. The promoter of this gene is frequently hypermethylated in these cancer tissues, although the hypermethylation does not appear to be the cause of the reduced expression of this gene. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015],
UniProt
Q96PB8
Swiss Prot
Q96PB8
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human LRC3B AA range: 115-165
Target
LRC3B
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Membrane ; Single-pass membrane protein .
Gene ID (Human)
116135

UniProtKB · Q96PB8

Leucine-rich repeat-containing protein 3B

LRC3B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96PB8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LRRC3B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q5M8T0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

Glycoprotein

Domain

Leucine-rich repeatRepeatSignalTransmembraneTransmembrane helix

Cellular component

Membrane

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