Protease-Activated Receptor-1, PAR-1 Agonist

Protease-Activated Receptor-1, PAR-1 Agonist

• CAS Number: 141136-85-8
• UNSPSC Description: Protease-Activated Receptor-1, PAR-1 Agonist is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist corresponds to PAR1 tethered ligand and which can selectively mimic theactions of thrombin via this receptor[1][2].
• Target Antigen: Protease Activated Receptor (PAR)
• Type: Peptides
• Related Pathways: GPCR/G Protein
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/protease-activated-receptor-1-par-1-agonist.html
• Purity: 98.34
• Solubility: H2O : ≥ 12.5 mg/mL
• Smiles: O=C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(O)=O)=O)=O)=O)=O)[C@H]([C@H](O)C)N
• Molecular Weight: 762.90
• References & Citations: [1]Stefanie Gödecke, et al. Thrombin-induced ATP release from human umbilical vein endothelial cells. Am J Physiol Cell Physiol. 2012 Mar 15;302(6):C915-23.|[2]Heider I, et al. PAR1-type thrombin receptor stimulates migration and matrix adhesion of human colon carcinoma cells by a PKCepsilon-dependent mechanism. Oncol Res. 2004;14(10):475-482.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
• Clinical Information: No Development Reported