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Spironolactone (Standard)

CAT: 0804-HY-B0561R-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0561R-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Spironolactone (Standard) is the analytical standard of Spironolactone. This product is intended for research and analytical applications. Spironolactone (SC9420) is an orally active aldosterone mineralocorticoid receptor antagonist with an IC50 of 24 nM. Spironolactone is also a potent antagonist of androgen receptor with an IC50 of 77 nM. Spironolactone promotes autophagy in podocytes[1][2][3].
CAS Number
52-01-7
Product Name Alternative
SC9420 (Standard)
UNSPSC
12352005
Hazard Statement
H351-H360-H373
Target
Androgen Receptor; Autophagy; Mineralocorticoid Receptor; Reference Standards
Type
Reference Standards
Related Pathways
Autophagy; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/spironolactone-standard.html
Purity
98.55
Smiles
C[C@@]12[C@](OC3=O)(CC3)CC[C@@]1([H])[C@@]([C@@H](CC4=CC5=O)SC(C)=O)([H])[C@]([C@]4(CC5)C)([H])CC2
Molecular Formula
C24H32O4S
Molecular Weight
416.57
Precautions
P260-P280-P405-P501
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
Launched

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